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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7356 | PTP1B-IN-1 | PTP1B inhibitor | Phosphatase |
PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM) | |||
T4256 | PTP1B-IN-2 | Phosphatase | |
PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM). | |||
T12579 | RAMB4 | PTP1B-IN-9 | Proteasome |
RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity. | |||
T4340 | SPI-112 | Phosphatase | |
SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2. | |||
T24073 | PTP1B-IN-4 | NUN 17724,PTP1B-inhibitor-2,PTP1B IN 2,PTP1B-IN-2,PTP1B-inhibitor-4,FRJ,PTP1B inhibitor 4,NUN17724,PTP1B inhibitor 2,PTP1BIN2,NUN-17724 | Phosphatase |
PTP1B-IN-4 (NUN-17724) is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes. | |||
T9921 | Infliximab | TNF | |
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis. | |||
T23133 | Pentamidine | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal | |
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. | |||
T7704 | KY-226 | Phosphatase | |
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,) | |||
T28410 | PHPS1 | PHPS-1,PHPS 1 | Phosphatase |
PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines. | |||
T1654 | Pentamidine isethionate | Pentamidine isethionate salt,Pentamidine diisethionate | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent. | |||
T23132 | Pentamidine dihydrochloride | MP-601205 dihydrochloride | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypanosoma brucei, Leishmania spp., and Babesia spp.) and fungi... | |||
T22276 | Bis(maltolato)oxovanadium(IV) | BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) | Phosphatase , Others |
Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i... | |||
T12578 | (E,E)-RAMB4 | PTP1B-IN-8 | Phosphatase |
PTP1B-IN-8 is a potent and selective inhibitor of protein tyrosine phosphatase-1B (PTP1B). | |||
T9938 | RA371 | EX-A4742 | Others |
RA371 (EX-A4742) is a derivative of PTP1B-IN-8, an inhibitor of PTP1B. | |||
T12577 | PTP1B-IN-3 | Phosphatase | |
PTP1B-IN-3 is a selective and potent PTP1B inhibitor with anticancer activity that inhibits PTP1B and TCPTP.PTP1B-IN-3 is used in the study of diabetes. | |||
T67893 | PTP1B-IN-22 | Phosphatase | |
PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes. | |||
T7381 | TCS 401 | Phosphatase | |
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 µM) | |||
T7084 | 2-Bromo-4'-hydroxyacetophenone | SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide | Phosphatase |
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH... | |||
TN1990 | Norathyriol | Akt , DNA/RNA Synthesis , AMPK , PPAR | |
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability. | |||
TN1956 | Mulberrofuran G | Phosphatase , HBV , Glucosidase | |
Mulberrofuran G, isolated from Morus alba L., has anti-hepatitis B virus activity and protects against ischemic injury-induced cell death. Mulberrofuran G is a dual inhibitor of PTP1B and alpha-glucosidase for use in the... |